USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P04080 USC-OGP 2-DE database:  P04080 P04080 General information about the entry View entry in simple text format Entry name CYTB_HUMAN Primary accession number P04080 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Cystatin-B; AltName: Full=CPI-B; AltName: Full=Liver thiol proteinase inhibitor; AltName: Full=Stefin-B;. Gene name Name=CSTB Synonyms=CST6, STFB Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1332: pI=6.89; Mw=16684 Cross-references UniProtKB/Swiss-Prot P04080; CYTB_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CYTB_HUMAN Primary accession number P04080 Sequence was last modified on  October 1, 1996 (version 2) Annotations were last modified on  March 15, 2017 (version 194) Name and origin of the protein Description RecName: Full=Cystatin-B; AltName: Full=CPI-B; AltName: Full=Liver thiol proteinase inhibitor; AltName: Full=Stefin-B; Gene name Name=CSTB Synonyms=CST6, STFB Encoded on Name=CSTB; Synonyms=CST6, STFB Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Epilepsy; Nucleus; Protease inhibitor; Reference proteome; Thiol protease inhibitor. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U46692; AAA99014.1; -; Genomic_DNA EMBL L03558; AAA35727.1; -; mRNA EMBL AF208234; AAF44059.1; -; Genomic_DNA EMBL AP001752; BAA95541.1; -; Genomic_DNA EMBL BC003370; AAH03370.1; -; mRNA EMBL BC010532; AAH10532.1; -; mRNA CCDS CCDS13701.1; -; . PIR A01278; UDHUB; . RefSeq NP_000091.1; NM_000100.3; . UniGene Hs.695; -; . PDB 1STF; X-ray; 2.37 A; I=1-98 PDB 2OCT; X-ray; 1.40 A; A/B=1-98 PDB 4N6V; X-ray; 1.80 A; 0/1/2/3/4/5/6/7/8/9=8-98 PDBsum 1STF; -; . PDBsum 2OCT; -; . PDBsum 4N6V; -; . ProteinModelPortal P04080; -; . SMR P04080; -; . BioGrid 107858; 23; . IntAct P04080; 8; . MINT MINT-1504629; -; . STRING 9606.ENSP00000291568; -; . MEROPS I25.003; -; . TCDB 1.C.91.1.1; the stefin b pore-forming protein (stefin b) family; . iPTMnet P04080; -; . PhosphoSitePlus P04080; -; . SwissPalm P04080; -; . BioMuta CSTB; -; . DMDM 1706278; -; . EPD P04080; -; . PaxDb P04080; -; . PeptideAtlas P04080; -; . PRIDE P04080; -; . TopDownProteomics P04080; -; . DNASU 1476; -; . Ensembl ENST00000291568; ENSP00000291568; ENSG00000160213; . GeneID 1476; -; . KEGG hsa:1476; -; . CTD 1476; -; . DisGeNET 1476; -; . GeneCards CSTB; -; . GeneReviews CSTB; -; . HGNC HGNC:2482; CSTB; . HPA CAB047320; -; . HPA HPA017380; -; . HPA HPA058557; -; . MalaCards CSTB; -; . MIM 254800; phenotype; . MIM 601145; gene; . neXtProt NX_P04080; -; . OpenTargets ENSG00000160213; -; . Orphanet 308; Unverricht-Lundborg disease; . PharmGKB PA26984; -; . eggNOG ENOG410IZK7; Eukaryota; . eggNOG ENOG41121QW; LUCA; . GeneTree ENSGT00390000015607; -; . HOGENOM HOG000294175; -; . HOVERGEN HBG002292; -; . InParanoid P04080; -; . KO K13907; -; . OMA PHENRPL; -; . OrthoDB EOG091G12NK; -; . PhylomeDB P04080; -; . TreeFam TF333174; -; . Reactome R-HSA-6798695; Neutrophil degranulation; . ChiTaRS CSTB; human; . EvolutionaryTrace P04080; -; . GeneWiki Cystatin_B; -; . GenomeRNAi 1476; -; . PRO PR:P04080; -; . Proteomes UP000005640; Chromosome 21; . Bgee ENSG00000160213; -; . CleanEx HS_CST6; -; . CleanEx HS_CSTB; -; . ExpressionAtlas P04080; baseline and differential; . Genevisible P04080; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0005730; C:nucleolus; IDA:HPA; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:1904724; C:tertiary granule lumen; TAS:Reactome; . GO GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IDA:UniProtKB; . GO GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc; . GO GO:0002020; F:protease binding; IPI:BHF-UCL; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0008344; P:adult locomotory behavior; IEA:Ensembl; . GO GO:0010466; P:negative regulation of peptidase activity; IDA:BHF-UCL; . GO GO:0045861; P:negative regulation of proteolysis; IDA:UniProtKB; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . CDD cd00042; CY; 1; . InterPro IPR000010; Cystatin_dom; . InterPro IPR018073; Prot_inh_cystat_CS; . InterPro IPR001713; Prot_inh_stefinA; . Pfam PF00031; Cystatin; 1; . PRINTS PR00295; STEFINA; . SMART SM00043; CY; 1; . PROSITE PS00287; CYSTATIN; 1; .

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